Gene structure, intracellular localization, and functional roles of sterol carrier protein-2
AM Gallegos, BP Atshaves, SM Storey… - Progress in lipid …, 2001 - Elsevier
Since its discovery three decades ago, sterol carrier protein-2 (SCP-2) has remained a
fascinating protein whose physiological function in lipid metabolism remains an enigma. Its
multiple proposed functions arise from its complex gene structure, post-translational
processing, intracellular localization, and ligand specificity. The SCP-2 gene has two
initiation sites coding for proteins that share a common 13 kDa SCP-2 C-terminus:(1) One
site codes for 58 kDa SCP-x which is partially post-translationally cleaved to 13 kDa SCP-2 …
fascinating protein whose physiological function in lipid metabolism remains an enigma. Its
multiple proposed functions arise from its complex gene structure, post-translational
processing, intracellular localization, and ligand specificity. The SCP-2 gene has two
initiation sites coding for proteins that share a common 13 kDa SCP-2 C-terminus:(1) One
site codes for 58 kDa SCP-x which is partially post-translationally cleaved to 13 kDa SCP-2 …
